PCE is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below: Upper respiratory tract infections of mild to moderate degree caused by Streptococcus pyogenes, Streptococcus pneumoniae, or Haemophilus influenzae. Lower respiratory tract infections of mild to moderate severity caused by Streptococcus pneumoniae or Streptococcus pyogenes. Listeriosis caused by Listeria monocytogenes. Pertussis (whooping cough) caused by Bordetella pertussis.Respiratory tract infections due to Mycoplasma pneumoniae. Skin and skin structure infections of mild to moderate severity caused by Streptococcus pyogenes or Staphylococcus aureus. Diphtheria iInfections due to Corynebacterium diphtheriae. Erythrasma infections due to Corynebacterium minutissimum. Syphilis caused by Treponema pallidum. Intestinal amebiasis caused by Entamoeba histolytica. Acute pelvic inflammatory disease caused by Neisseria gonorrhoeae. Legionnaires’ Disease caused by Legionella pneumophila, etc..