COSMEGEN is an actinomycin indicated for the treatment of:
• adult and pediatric patients with Wilms tumor, as part of a multi-phase,
combination chemotherapy regimen.
• adult and pediatric patients with rhabdomyosarcoma, as part of a multiphase,
combination chemotherapy regimen.
• adult and pediatric patients with Ewing sarcoma, as part of a multi-phase,
combination chemotherapy regimen.
• adult and pediatric patients with metastatic, nonseminomatous testicular
cancer, as part of a multi-phase, combination chemotherapy regimen.
• post-menarchal patients with gestational trophoblastic neoplasia, as a single
agent or as part of a combination chemotherapy regimen.
• adult patients with locally recurrent or locoregional solid malignancies, as a
component of palliative or adjunctive regional perfusion.
